Successfully treated advanced esophageal cancer with left axillary lymph node metastasis and synchronous right breast cancer: a case report

نویسندگان

  • Yuji Akiyama
  • Takeshi Iwaya
  • Yoshihiro Shioi
  • Fumitaka Endo
  • Kazushige Ishida
  • Masahiro Kashiwaba
  • Koki Otsuka
  • Hiroyuki Nitta
  • Keisuke Koeda
  • Masaru Mizuno
  • Yusuke Kimura
  • Akira Sasaki
چکیده

The incidence of double cancer of the esophagus and breast is rare, and axillary lymph node metastasis (ALM) in esophageal cancer is also very rare. We report a case of advanced esophageal cancer with left ALM and synchronous right breast cancer. A 64-year-old woman was admitted to our hospital with dysphagia. The clinical diagnosis was esophageal cancer (T3N0M1 stage IV) and right breast cancer (T1cN0M0 stage I). She was initially treated with triple chemotherapy with docetaxel, cisplatin, and 5-fluorouracil. The primary lesion in the esophagus achieved almost complete response as assessed by esophageal endoscopy. A computed tomography scan showed that the left ALM reduced in size and that stable disease was achieved for the right breast cancer. She underwent partial mastectomy of the right breast and bilateral axillary lymph node dissection. The histopathological diagnosis of the breast cancer was T1cN1M0 stage IIA. The lymph nodes from the left axilla contained metastatic cells from the squamous cell carcinoma of the esophagus. Complete response was achieved for the primary lesion in the esophagus following chemoradiotherapy (CRT), and the patient has been relapse free 2 years after treatment. Thus, we report the successful treatment of synchronous double cancers of the esophagus with left ALM and right breast by combination therapy with chemotherapy, CRT, and surgery.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Axillary lymph node metastasis in medullary thyroid carcinoma: A case report

Introduction: Medullary thyroid cancer (MTC) is an uncommon neoplasm originating from parafollicular C cells. Distant metastasis in MTC, such as axillary node involvement, is extremely rare.  Case Report: The present study describes a known case of MTC with axillary lymph node metastasis in a 31-year-old woman. In 2010, she underwent total thyroidectomy and right-sided modified radical neck dis...

متن کامل

Is It Contralateral Axillary Metastasis or Occult Breast Cancer?: A Confusing Case Report.

We report the case of a 43-year-old woman with primary left breast cancer presenting metastatic lymphadenopathy in the contralateral axilla. This patient represents a diagnostic and therapeutic challenge because primary breast cancer, occult contralateral breast cancer, and extra-mammary primary lesion can all be the source of the contralateral axillary metastasis. Left breast-conserving surger...

متن کامل

Significance of histopathological features of breast carcinoma and its correlation for desision of future therapy

Breast cancer is one of the most common malignancies among women and considered as the first caise of mortality in females suffering from malignant processes.axillary lymph node metastasis (ALNM)is the most important predictor of survival in patient with breast carcinoma.the purpose of this study was to determine the association between the incidence of ALNM and morphologic criteria by univaria...

متن کامل

Dissection axillary lymph node count in patient with breast cancer followed by neoadjuvant therapy

Introduction: Breast cancer is the most common cancer and the second cause of death in women. It is essential to have the highest level of confidence in axillary staging assessment. Many surgeons and pathologists believe that fewer lymph nodes are present in axillary dissection specimens of women treated by neoadjuvant chemotherapy. Consequently, the purpose of this study was to compare the lym...

متن کامل

Bilateral male breast cancer: a case presenting with synchronous invasive lobular carcinoma and invasive ductal carcinoma

Synchronous bilateral male breast cancer is a very rare entity and invasive lobular carcinoma is less common in male breast cancer (MBC) than in female breast cancer (FBC). A 51-year-old man presented with a palpable mass in the left breast was finally diagnosed synchronous bilateral MBC, one an invasive lobular carcinoma and the other an invasive ductal carcinoma. It remains a matter of debate...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 1  شماره 

صفحات  -

تاریخ انتشار 2015